Hamilton held off a mid-race challenge from Red Bull's Max Verstappen to register a record-equalling fourth triumph at the floodlit Marina Bay Street Circuit track, while Vettel finished third to slip further behind in the title race.
Ferrari's Sebastian Vettel, winner of 52 races, has gone more than a year since he tasted victory at last year's Belgian race.
Britain's Lewis Hamilton eased his Mercedes to a dominant victory in the German Formula One Grand Prix on Sunday and secured his fourth victory in a row.
Hamilton has won half of the season's 20 races so far, propelling his team to an unprecedented sixth successive title double, but Brazil was a disappointing weekend with Valtteri Bottas retiring.
Sebastian Vettel's Formula One title bid could suffer a further setback after a bizarre post-race incident at the Malaysian Grand Prix on Sunday.
Seven-time world champion Lewis Hamilton will be staying in Formula One for the next two years at least after he and Mercedes announced a contract extension on Saturday.
Formula One has said it hopes to get the season started some time in the European summer with a reduced calendar of 15-18 races.
Lewis Hamilton surpassed Ayrton Senna's career haul of 65 pole positions in Formula One as he edged Mercedes team mate Valtteri Bottas to secure top spot the Azerbaijan Grand Prix on Saturday.
The race has been won from pole eight times out of 11 editions.
IMAGES from the Silverstone F1 GP on Sunday
Lewis Hamilton took pole position at the Italian Grand Prix for the third year in a row on Saturday with Mercedes team mate and title rival Nico Rosberg joining the Briton on the front row of the grid.
Lewis Hamilton is on course for his most successful campaign yet and can become only the third driver after Michael Schumacher and Sebastian Vettel to win 13 times in a season.
From bloody noses to sparks on the race track, Rediff.com has the best pictures from the last week snapped right here...
Formula One world champion Lewis Hamilton took pole for Mercedes at the season-opening Australian Grand Prix.
Ferrari were the fastest in pre-season testing, raising suspicions that their new SF70H car has closed the chasm between Mercedes and the rest.
Team by team prospects for the 2016 Formula One season.
'It doesn't really make a big difference if I go and drive like I do right now because I have already lost so much through the year. I can't give up because you never know what can happen. It's unlikely but you never know'
Lewis Hamilton won the Mexican Formula One Grand Prix on Sunday, his landmark 51st career victory cutting Mercedes team mate Nico Rosberg's overall lead to 19 points and keeping the German waiting for a first title. The pole-to-flag victory was the triple world champion's eighth of the season and put him level with France's Alain Prost in the all-time lists of winners. Only Michael Schumacher (91) has more. Rosberg, who would have clinched the title had he won and Hamilton finished 10th or lower, crossed the line 8.354 seconds behind to anchor champions Mercedes to a sixth one-two finish of the season.
A glaring error by Ferrari denied Charles Leclerc the chance to shine at home, with the 21-year-old failing to make it through the first phase and qualifying only 16th after going fastest in final practice.
Nico Rosberg eased to victory at the Japanese Grand Prix on Sunday with a drive that handed Mercedes their third straight constructors championship and extended the German's lead in his pursuit of a maiden Formula One title.
Sebastian Vettel's expletive-laden radio rants betray his frustration at Ferrari's fading form, according to his former Red Bull team mate Daniel Ricciardo and predecessor Fernando Alonso.
Formula One legend, Niki Lauda, thinks it's going to be a tighter fight between them, because the latter wants to make sure now he can beat the Briton.
Lewis Hamilton can become only the third driver to win 50 grands prix when Formula One returns from its month-long August break and gets back to business at Sunday's Belgian Grand Prix.
'We've still got work to do to get both cars home in the points. We'll take positives from today, but we're trying to find a bit more every weekend.'
The pole was a record-extending 88th of Hamilton's career and fifth of the season.
Charles Leclerc seized pole position for the Belgian Formula One Grand Prix on Saturday ahead of team mate Sebastian Vettel who completed a front row lockout for Ferrari.
George Russell will replace Valtteri Bottas and race for Mercedes next season in an all-British line-up with seven times world champion Lewis Hamilton, the Formula One team said on Tuesday.
Renault's Chinese test driver Guanyu Zhou won a virtual Bahrain Grand Prix on Sunday as Formula One sought to entertain fans with esports action in a season stalled by the spreading coronavirus. The first seven rounds of the real championship have been cancelled or postponed, including the showcase Monaco Grand Prix, and it remains to be seen how many there will be ultimately.
Valtteri Bottas won the battle but Lewis Hamilton won the war, securing his sixth Formula One world championship on Sunday, despite finishing second to his Mercedes team mate at the US Grand Prix.
Valtteri Bottas seized his first pole position of the Formula One season in Austria on Saturday with Mercedes team mate and world championship leader Lewis Hamilton having to settle for second.
Lewis Hamilton won his home British Grand Prix for the fourth year in a row on Sunday while Ferrari's Sebastian Vettel suffered a penultimate lap puncture that slashed his championship lead to a single point.
Michael Schumacher's son Mick is '100 percent' certain to make it to Formula One and when he does it will be great for the sport, world champion Lewis Hamilton said.
Ferrari carry burden of history and expectation as they unveil 2022 car.
The Finn was a mere 0.006 of a second quicker than the five times world champion as the two Silver Arrows once again locked out the front row of the grid on a cloudy afternoon at Silverstone.
The victory was a landmark 70th for the Briton, who is well on his way to a fifth title and is now 21 wins behind the all-time record of 91 held by seven times champion Michael Schumacher.
'I could never have dreamed of being where I am today.'
World champion Lewis Hamilton took pole for Mercedes in qualifying on Saturday for Formula One's season-opening Australian Grand Prix.
Hamilton said he only realised the significance of what he had done when he came into the pitlane after taking the chequered flag.
The sky's the limit for George Russell after the British youngster's stellar performance
Perez, who vaulted to fourth in the overall standings after Sunday's race, is the first Mexican driver to win a race since Pedro Rodriguez took victory in the 1970 Belgian Grand Prix.
